Combination of GD2-directed bispecific trifunctional antibody therapy with Pd-1 immune checkpoint blockade induces anti-neuroblastoma immunity in a syngeneic mouse model.

Front Immunol · 2022 · PMC9869131 · PMID 36700232

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Interestingly, flow cytometric analysis showed a trend towards lower T cell infiltration in both groups receiving combined treatment with tumor vaccination and SUREK trAb with or without administration of Pd-1 blocking antibody ( Supplementary Figures 6A, B ).

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