nigra , they had more reactive oxidative species and a higher concentration of carbonylated proteins in the brain; bi-genic mice also showed a trend for more nitrotyrosinated proteins.
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The sentences
When we measured GSH concentrations in prkn −/− murine brains using the HPLC method, we recorded a small trend for a rise in relative GSH levels (and lowering of GSSG; Fig. 4 d), as seen by the Tietze method above.