Gut-derived β-amyloid: Likely a centerpiece of the gut-brain axis contributing to Alzheimer's pathogenesis.

Gut Microbes · 2023 · PMC9872956 · PMID 36683147

Europe PMC DOI

hedged sentences

0.1900

closest p · 3.8× alpha

0.1900

boldest claim

The sentences

showed a trendP = 0.19not close (p > 0.1)

2A-B ), the level of APP showed a trend toward increase ( Figure 2a-b , P = 0.19), and the protein level of Aβ42 was significantly higher in 12-month-old WT mice ( Figure 2a-b , P < 0.05).

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an increasing trendno p-value reported

The results showed that the expression level of colonic BACE1 was significantly higher in the WT mice transplanted with feces of APP/PS1 mice (FMT-AD) than that of FMT-con ( Figure 4e & f , P < 0.05) and the expression level of APP showed an increasing trend although not statistically significant ( Figure 4e & f , P = 0.1221).

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