In PALOMA-3, 42 the final pre-specified survival analysis did not reach statistical significance and in the recently reported PALOMA-2 analysis OS advantage was non-significant, 23 with a high percentage of missing data.
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The likelihood of being helped or harmed as a patient-centred tool to assess cyclin dependent kinase 4/6 inhibitors clinical impact and safety in metastatic breast cancer: a systematic review and sensitivity-analysis.
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