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Determination of HMGB1 in hepatitis B virus-related acute-on-chronic liver failure patients with acute kidney injury: Early prediction and prognostic implications.

Front Pharmacol · 2022 · PMC9880762 · PMID 36712653

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From Figure 5A , discrimination was relatively higher for HMGB1 [0.727 (95% CI: 0.648–0.807) than the AUROC of the MELD [0.663 (95% CI: 0.574–0.751)], Child-Pugh [0.722 (95% CI: 0.645–0.800)], and CLIF-C ACLF [0.708 (95% CI: 0.627–0.789)] scores, although these differences did not reach statistical significance.

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