When comparing the entire cohort of DOC patients against awake healthy controls, connectome harmonic decomposition revealed an energy signature with significant similarity to the signature of moderate propofol anaesthesia (Spearman’s ρ = 0.60, CI 95% [0.13, 0.85], p = 0.020), although most frequency-specific differences did not reach statistical significance after correction for multiple comparisons (Fig. 3g ).
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Distributed harmonic patterns of structure-function dependence orchestrate human consciousness.
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