The potential of using circulating tumour cells and their gene expression to predict docetaxel response in metastatic prostate cancer.

Front Oncol · 2022 · PMC9885040 · PMID 36727071

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.6600

boldest claim

The sentences

a trend towards significancep= 0.064so close (0.05 < p ≤ 0.1)

A CRS comprised of mesenchymal-CTC number and serum ALP levels as CRS-MA= 0.3599 * mesenchymal-CTC number + 0.002037 * ALP, increased the AUC to 0.69, however with only a trend towards significance (p= 0.064) ( Figure 2D ).

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showed a trendp= 0.66not close (p > 0.1)

Neither serum PSA or ALP levels significantly differentiated patients based on OS, although ALP showed a trend towards significance (AUC= 0.55, p= 0.66; AUC= 0.73, p= 0.072, respectively) ( Figure 7A ).

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