Indeed, the functional integration of environmental materials (e.g., silicon, iron in hemes, batrachotoxins, stones, hemes in haemoglobin, plastids) engenders novelty with different kinds of evolutionary effects, some of them clearly significant.
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The sentences
These two cases of “developmental entrenchment” are arguably significant evolutionary novelties in the history of the respective lineages (West-Eberhard 2003 , p. 502–3).