The loss of cardiac SIRT3 decreases metabolic flexibility and proteostasis in an age-dependent manner.

Geroscience · 2023 · PMC9886736 · PMID 36460774

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closest p · 1.0× alpha

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boldest claim

The sentences

failed to reach statistical significancep < 0.05actually significant

In comparison to the proteomics results, Western blot analysis revealed a decrease PDH (PDHA1) and showed that there was a trend towards decreased phosphorylated PDH at 10 months but failed to reach statistical significance (predetermined to be p < 0.05; Fig. 4 G ).

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