Copper intrauterine device increases vaginal concentrations of inflammatory anaerobes and depletes lactobacilli compared to hormonal options in a randomized trial.

Nat Commun · 2023 · PMC9886933 · PMID 36717556

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0.1600

closest p · 3.2× alpha

0.1600

boldest claim

The sentences

did not reach statistical significanceP = 0.16not close (p > 0.1)

At the 6-month visit, women randomized to DMPA-IM also had lower Shannon diversity than women randomized to LNG implant, although this did not reach statistical significance (ANCOVA adjusted P = 0.16; Fig. 1c ).

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