A recent retrospective, non-randomised case series to evaluate the safety and efficacy of patients treated topically with ‘Benozzi’s method’ for presbyopia (ie, pilocarpine and diclofenac preservative-free eye-drops) from January 2011 to June 2018, showed a trend towards near vision spectacle independence. 59 Based on data from 910 participants (aged 40–59 years), baseline uncorrected near visual acuity (UNVA) over the 8-year period (as measured by Jaeger scale) improved from 4.74 (SD 1.53) to 1.36 (SD 0.48), while binocular uncorrected distance visual acuity remained stable (baseline 0.00 (SD 0.01) logMAR, 8 years 0.03 (SD 0.04) logMAR.
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