Neutrophil CEACAM1 determines susceptibility to NETosis by regulating the S1PR2/S1PR3 axis in liver transplantation.

These correlated negatively with the CC1-L/CathG ratio ( r = –0.2075, P = 0.2050; Figure 11B ) while showing a highly significant positive correlation with sAST ( r = 0.5107, P = 0.0009; Figure 11C ) and sALT ( r = 0.6360, P < 0.0001; Figure 11D ) at POD1.

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Of note, PMN DTR mice conditioned with CC1 -deficient neutrophils showed a trend toward higher (albeit not significant) serum transaminase release because of putative proinflammatory phenotype.

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