Differential angiogenesis of bone and muscle endothelium in aging and inflammatory processes.

On the contrary, an almost significant negative correlation was observed for the sprouting of mECs, (as shown in Fig. 3C : r 2 = 0.67, p = 0.08), suggesting a lower angiogenic potential in mECs derived from patients with higher systemic inflammation (Fig. 3f ).

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We found that bEC derived from grade 3 OA patients had a higher branch number and area sprout as compared to bEC derived from grade OA 2 patients, although the differences did not reach statistical significance (Supplementary Fig. 4 ).

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