Novel Lymphocyte-Independent Antitumor Activity by PD-1 Blocking Antibody against PD-1+ Chemoresistant Lung Cancer Cells.

The combination of Ab anti–PD-1 with CDDP showed a trend toward enhanced antitumor activity and delayed onset of chemoresistance, even if statistical significance was not reached ( n = 4. 37 vs. 102 mm 3 , P = 0.5; Fig. 5 C – E ).

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