The therapeutic age of the neonatal Fc receptor.

Nat Rev Immunol · 2023 · PMC9891766 · PMID 36726033

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nearly significantno p-value reported

In the arthrogryposis multiplex congenita model, the administration of FcRn antagonist to pregnant dams infused with human acetylcholine receptor-specific antibodies resulted in nearly significant decreases in pathogenic antibodies in the dams, and a major decrease of these antibodies in the fetuses 239 .

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