Conversely, RAD18, which plays a principal role in DNA damage repairment 26 ; and ARIH2, whose transcription predicts latency of acute myeloid leukemia (AML) 27 , tended to be negatively correlated with EYA4 ( r = -0.541, P = 0.069 and r = -0.537, P = 0.072), yet such correlation did not reach statistical significance.
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Tripartite motif containing 69 elicits ERK2-dependent EYA4 turnover to impart pancreatic tumorigenesis.
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