Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of <i>C9orf72</i> disease.

Proc Natl Acad Sci U S A · 2022 · PMC9894253 · PMID 36454749

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hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

Antibody treatment with ch α-GA 3 showed a trend ( P = 0.08) in favoring the colocalization of GA 50 -GFP with late endosomes compared to treatment with the IgG control.

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a nonsignificant trendno p-value reported

Mice treated with ch α-GA 1 and ch α-GP 1 antibodies also showed a nonsignificant trend toward improvement in this behavioral assay ( Fig. 4 D ).

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