Epistasis between promoter activity and coding mutations shapes gene evolvability.

Sci Adv · 2023 · PMC9897669 · PMID 36735790

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

only marginally significantP = 0.09so close (0.05 < p ≤ 0.1)

Although only marginally significant ( P = 0.09), E2R had higher activity than E2V, which corresponds to the slightly higher fitness observed for E2R in individual growth assays (fig.

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