We found that ATG9A, YTHDF3, EHD1, and ABHD5 were significantly downregulated in PD samples when compared to healthy, while AP2B1 showed a trend towards decreased expression (Fig. 7a–f ).
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Regulators of proteostasis are translationally repressed in fibroblasts from patients with sporadic and LRRK2-G2019S Parkinson's disease.
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