Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia.

Sci Rep · 2023 · PMC9905079 · PMID 36750708

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nominally significantno p-value reported

Two of the three most frequently identified genes in recent exome-wide association studies in unrelated individuals ( TREM2 and SORL1 ) were significantly associated with proxy AD/dementia in this study and the third gene ( ABCA7 ) was nominally significant.

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