Longer treatment intervals are associated with reduced treatment persistence in neovascular age related macular degeneration.

The proportion of visits with active MNV over the first 2 years, however, was significantly different amongst treatment interval groups, showing a clear trend of increase from the long interval to short interval groups from 44% of visits in the 12-week group to 75% in the 4-week group, although the > 12-week group had a higher proportion of active visits than the 12-week group (52%; global P < 0.001).

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