The ECC loss was observed to be more in diabetics but did not reach statistical significance in their series.[ 54 ] Kudva et al . later demonstrated a significantly greater ECC loss in diabetics at 1 and 3 months postoperatively, unrelated to HbA1c or duration of diabetes.[ 55 ] Increased rates of ECC (19.2%) have also been reported in uveitic cataracts at 6 months.[ 56 ] Cystoid macular edema (CME) A larger incision size, greater tissue trauma, and iris manipulation were found to be associated with increased chances of breakdown of the blood-retinal barrier in MSICS in comparison to PE.
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