A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency.

PLoS Pathog · 2023 · PMC9907829 · PMID 36706161

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showed a trendno p-value reported

PRC2 has also been previously reported to silence HIV-1 transcription [ 8 , 10 ] and members of the complex including EZH2 , the catalytic component, and SUZ12 and EED showed a trend of enrichment in our screen ( Fig 2B and S2 Table ).

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