[1] for their comments on our study in which we compared the characteristics of the patients hospitalised at our coronavirus disease 2019 (COVID-19) referral centre in Milan, Italy, during the last three waves of COVID-19, and showed a trend towards a reduction in the number of severely ill COVID-19 patients and a progressive increase in the proportion of SARS-CoV-2 positive patients admitted for reasons other than COVID-19 (up to 40% in July 2022, when SARS-CoV-2 Omicron BA.2 and BA.5 began to spread in Italy) [2] .
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Evolution of the SARS-CoV-2 epidemic: From genomic surveillance to new health needs.
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