Neprilysin Inhibitors in Heart Failure: The Science, Mechanism of Action, Clinical Studies, and Unanswered Questions.

JACC Basic Transl Sci · 2023 · PMC9911324 · PMID 36777165

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did not reach statistical significanceno p-value reported

69 Based on an early analysis of 110 pediatric patients, the reduction in NT-proBNP over 12 weeks was 44% and 33% in the sacubitril-valsartan and enalapril groups, respectively, but it did not reach statistical significance.

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