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The effects of Sodium-glucose cotransporter 2 inhibitors on adipose tissue in patients with type 2 diabetes: A meta-analysis of randomized controlled trials.

Front Endocrinol (Lausanne) · 2023 · PMC9911550 · PMID 36777342

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Blood lipids According to the meta-analysis, triglycerides (WMD = -24.41 mg/dl, 95% CI: -45.79 ~ -3.03, P = 0.03) were significantly lower and HDL cholesterol (WMD = 1.63 mg/dl, 95% CI: 0.62 ~ 2.64, P = 0.002) was significantly higher in SGLT2 inhibitor-treated patients as compared to controls, while total cholesterol and LDL cholesterol failed to reach statistical significance ( Table 3 ). 4.

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