Effects of Oral Levodopa on Balance in People with Idiopathic Parkinson's Disease.

J Parkinsons Dis · 2023 · PMC9912739 · PMID 36617752

Europe PMC DOI

hedged sentences

0.0400

closest p · 0.8× alpha

0.0400

boldest claim

The sentences

marginally statistically significantp = 0.04actually significant

Of all the outcomes reported for step initiation only velocity-based outcomes in ML direction showed a small but marginally statistically significant effect favoring Levodopa ON state (SMD = –0.28 [–0.54; –0.02], Z = 2.09 [ p = 0.04], I 2 = 0% [ p = 0.93]).

also in 1,110 other papers

showed a trendno p-value reported

All other clinical balance tests, including the Mini Balance Evaluation System Test, the Pull Test, and the Timed Up and Go test showed a trend towards improvement with Levodopa but these differences were not statistically significant.

also in 53,322 other papers

a positive trendno p-value reported

Nevertheless, the results of this review and pilot meta-analysis indicate that oral Levodopa tends to improve performance as measured by clinical balance scales and shows a positive trend towards increased anterior-posterior and mediolateral sway during step initiation.

also in 11,005 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.