Development of a Novel Low-Calorie Lime Juice-Based Prebiotic Beverage Using a Combined Design Optimization Methodology.

The highly significant model ( p ≤ 0.001) and non-significant lack of fit ( p > 0.05) showed the adequacy of models developed for all responses used to constitute the correlation between variables and responses.

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Up to a critical LEO proportion in the mixture, flavor acceptance increased, while at higher ratios, a negative trend occurred ( Figure 1 b and Figure 2 b).

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