highly significantp < 0.001
Interestingly, there was a modest, but statistically highly significant increase in the HW/BW ratio of Gnpat KO compared with WT mice (HW/BW (×10 3 ) ± SD: WT: 4.577 ± 0.789, n = 102; KO: 5.187 ± 0.925, n = 86; p < 0.001 (two-tailed Student’s t -test)), which may be an indicator of hypertrophy.