Sustained Cytotoxic Response of Peripheral Blood Mononuclear Cells from Unvaccinated Individuals Admitted to the ICU Due to Critical COVID-19 Is Essential to Avoid a Fatal Outcome.

Int J Environ Res Public Health · 2023 · PMC9915056 · PMID 36767310

Europe PMC DOI

hedged sentences

0.0571

closest p · 1.1× alpha

0.0571

boldest claim

The sentences

did not achieve significancep = 0.0571so close (0.05 < p ≤ 0.1)

From Week 4, PBMCs from individuals of both groups showed an increase in the levels of cells with NKT phenotype (CD3+CD56+) that was 4.17-fold higher in the PBMCs from the individuals of the Exitus group at Week 6, although this difference did not achieve significance ( p = 0.0571; Cohen’s d = 3.15) ( Figure 5 A).

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did not reach statistical significanceno p-value reported

This increase was slightly higher when cells were treated with IL-15 in both groups, although data did not reach statistical significance either ( Figure 5 A).

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