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Mechanobiology of the Human Intervertebral Disc: Systematic Review of the Literature and Future Perspectives.

Int J Mol Sci · 2023 · PMC9917554 · PMID 36769050

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a significant trendno p-value reported
It is important to note a significant trend towards increasing complexity in study designs and techniques employed in more recent studies compared to older studies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.