The Role of Genetics in the Development and Pharmacotherapy of Depression and Its Impact on Drug Discovery.

Another gene-based association analysis chose 14 polymorphisms as the suggested markers for an antidepressant response, however, on further evaluation they did not reach statistical significance in the case-control study [ 32 ].

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Studies of that type raise the possibility that the processes of energy generation and oxidative damage could be considered significant targets for the treatment of mood disorders.

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