A Cross-Species Analysis Reveals Dysthyroidism of the Ovaries as a Common Trait of Premature Ovarian Aging.

In addition, an increasing trend was detected for the Oatp1c1 transporter ( Figure S3i ).

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In fact, both transcripts were reduced in C57BL/6J females fed a Ketogenic diet and showed a trend towards downregulation in females fed the American diet ( Figure 1 g,h), whereas they were both induced in FVB/NJ females fed with these diets ( Figure 1 i,j).

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Thrb mRNA was reduced in females exposed to 1 mg/kg/day CPF and increased at higher doses ( Figure 5 i), whereas Thra mRNA showed a decreasing trend at any dose ( Figure S3h ).

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