Malvidin-3-<i>O</i>-Glucoside Ameliorates Cadmium-Mediated Cell Dysfunction in the Estradiol Generation of Human Granulosa Cells.

In terms of gene expression levels, gene expression was significantly higher for Hsd3b , comparable across groups for Hsd17b1 , significantly lower for Hsd17b12 , consistent for Hsd17b7 for both gene and protein expression, and lowered, followed by an increasing trend for Gper1 ( Figure 7 E–I). 4.

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Surprisingly, the transcriptomic data showed that the expression of HSD17B7 showed a trend of increasing after Cd exposure and decreasing after M3G treatment; the results of RT-qPCR and WB experiments supported this trend as well.

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