Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects.

J Immunother Cancer · 2023 · PMC9923271 · PMID 36759012

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did not reach statistical significanceno p-value reported

We rechallenged three mice cured of ID8agg by chlorambucil, showing a trend to tumor protection that did not reach statistical significance ( figure 5C ) possibly due to low numbers of available cured mice.

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