Barely Significant
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Higher Dose Oral Fluconazole for the Treatment of AIDS-related Cryptococcal Meningitis (HIFLAC)-report of A5225, a multicentre, phase I/II, two-stage, dose-finding, safety, tolerability and efficacy randomised, amphotericin B-controlled trial of the AIDS Clinical Trials Group.

PLoS One · 2023 · PMC9925064 · PMID 36780493

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I have added the following point in the discussion: “Amphoterecin B appears to be superior to higher doses of FCZ but did not reach statistical significance.

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