Indocyanine-enhanced mouse model of bleomycin-induced lung fibrosis with hallmarks of progressive emphysema.

Am J Physiol Lung Cell Mol Physiol · 2023 · PMC9925167 · PMID 36625471

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partially significantno p-value reported

As in the case of RAW 264.7 cells, loss of cell viability was paralleled by a marked, albeit only partially significant, upregulation of the proapoptotic FAS and CASP7 mRNAs, which was only detectable in BLM + ICG-treated cells (Supplemental Fig.

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a clear trendno p-value reported

Multiple inflammation and fibrosis biomarkers were found to be increased in the bronchoalveolar lavage fluid of BLM- and BLM + ICG-treated animals, but with a clear trend toward a much stronger increase in the latter group.

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