Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling.

J Clin Invest · 2023 · PMC9927934 · PMID 36548088

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showed a trendno p-value reported

L973F-IR knockin mice, on the other hand, showed a trend toward an increase in body length ( Figure 8B ), and tibial length was significantly increased compared with that in controls ( Figure 8C ).

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