Trivalent mosaic or consensus HIV immunogens prime humoral and broader cellular immune responses in adults.

Boost-targeting responses against CM235 were triggered more frequently by the mosaic prime (67% of vaccinees made a CD4 + T cell response that recognized CM235, 33% made a CD8 + T cell response) than by either the CON-S (33% CD4 + , 29% CD8 + ) or the Nat-B prime (36% CD4 + , 24% CD8 + ), but this did not reach statistical significance ( Figure 5 ).

also in 111,027 other papers