Multivariate analysis of variegated expression in Neurons: A strategy for unbiased localization of gene function to candidate brain regions in larval zebrafish.

We found a highly significant association between signal in the DCR6 and escape bias overall (main effect of phenotype p<0.0001, with significant within-genotype effects after controlling for multiple comparisons in CaSR +/+ and CaSR p190/p190 groups) ( Fig 4A ).

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This near-significant result underlines the importance of choosing an unbiased method, like LASSO regression, to identify the most promising brain regions for further analysis.

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