Localized strain characterization of cardiomyopathy in Duchenne muscular dystrophy using novel 4D kinematic analysis of cine cardiovascular magnetic resonance.

We found that peak E ll in DMD CMP patients was not significantly different from that of healthy controls in any region, though our results approached significance in the posterior portion of the LV ( p = 0.050, AUC = 0.66), with a modest average difference in posterior peak E ll between groups.

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E cc systolic strain rate also had the greatest difference between DMD CMP and control subjects at the base ( p < 0.001, AUC = 0.95), though mid-ventricular, apical, and global strain were also highly significant.

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