Analysis of 3.5 million SARS-CoV-2 sequences reveals unique mutational trends with consistent nucleotide and codon frequencies.

Virol J · 2023 · PMC9936480 · PMID 36812119

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a negative trendno p-value reported

calculated changes in CAI from December 2019 to September 2021, finding a negative trend in CAI when all genes are concatenated.

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