As shown in Figure S3 , there was a trend for higher expression of TGM2 in islets harboring the protective rs2076380-GG genotype compared to islets harboring the risk allele in heterozygosis (rs2076380-AG) or homozygosis (rs2076380-AA), although the differences did not reach statistical significance, probably due to the limited number of islets.
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A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of <i>TGM2</i> gene in pancreatic beta cells.
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