Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1<sup>R206H</sup> -Specific Human Cellular and Zebrafish Models.

J Bone Miner Res · 2022 · PMC9950781 · PMID 36153796

Europe PMC DOI

hedged sentence

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

approached significancep = 0.063so close (0.05 < p ≤ 0.1)

Similar findings were seen in ACVR1 WT HEK 293T cells, although stimulation with AA approached significance ( p = 0.063) (Fig.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1&lt;sup&gt;R206H&lt;/sup&gt; -Specific Human Cellular and Zebrafish Models.

The sentences

Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1<sup>R206H</sup> -Specific Human Cellular and Zebrafish Models.