Indeed, when stratifying the patients according to this dichotomous cut-off, the difference was highly significant, p < 0.001 ( Figure 2 D); the median OS for the fit patients (4/16 died, 25%) was not reached, while the median OS for the unfit patients (82/104 died, 78.8%) was 12.1 months (IQR: 6.1–29.0).
Combining them with the AML-score for CR enhanced their predictive power, although not all of their combinations did so: the performance status and geriatric depression scales failed to reach statistical significance.
Min and colleagues showed, as in our study population, that in a clinically selected cohort for intensive chemotherapy, functional tests, such as the gait speed test and the sit and stand speed test may be significant tests for OS prediction.