Barely Significant
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Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19.

Pharmaceutics · 2023 · PMC9960594 · PMID 36839968

3
hedged sentences
0.2600
closest p · 5.2× alpha
0.3300
boldest claim

The sentences

a positive trendp = 0.26not close (p > 0.1)
Other laboratory parameters such as leucocytes registered a positive trend in both groups with a mean difference of 3.73 ± 7.214 10 9 /L in the treated group and 5.17 ± 7.66 10 9 /L in controls ( p = 0.26 and p = 0.52, respectively).

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a decreasing trendp = 0.33not close (p > 0.1)
TSAT also increased in the treated by a mean of 16.67 ± 15.25% ( p = 0.044) but followed a decreasing trend in controls by a mean difference of −6.333 ± 6.122% ( p = 0.33).

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did not reach statistical significancep = 0.106not close (p > 0.1)
an increasing trendno p-value reported
IL-6 followed an increasing trend in both the treatment and control groups, with a mean difference of 674.6 ± 838.9 pg/mL in the treated and 341.3 ± 554.5 pg/mL in controls; however, this did not reach statistical significance ( p = 0.106 in treated and p = 0.552 in controls).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.