Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation.

J Funct Biomater · 2023 · PMC9961206 · PMID 36826910

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did not reach statistical significanceno p-value reported

Interestingly, the scaffolds adsorbed with either 4 μg BMP-2 or 2 μg PDGF-BB showed less MPO (as an indicator for neutrophils) and iNOS (as an indicator for pro-inflammatory macrophages) staining; albeit, this did not reach statistical significance due to the relatively low sample size ( Figure S4 ).

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