Needle-Free Devices and CpG-Adjuvanted DNA Improve Anti-HIV Antibody Responses of Both DNA and Modified Vaccinia Ankara-Vectored Candidate Vaccines.

Vaccines (Basel) · 2023 · PMC9965773 · PMID 36851255

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showed a trendno p-value reported

Administration of the DNA and MVA vaccines with the PharmaJet Stratis device also showed a trend towards increasing mean titres of neutralizing antibodies.

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a definite trendno p-value reported

There was also a definite trend towards increased mean titres of Tier 1A nAbs from Groups 1 to 3 after the first MVA inoculation with the use of the PharmaJet device (mean titres 336.4 DDM, 787.2 D*D*M, and 1614.6 D*D*M* or geometric mean titres 55.8 DDM, 294.4 D*D*M, and 398.6 D*D*M*. * = use of Pharmajet Stratis device).

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