Cytochalasin B Influences Cytoskeletal Organization and Osteogenic Potential of Human Wharton's Jelly Mesenchymal Stem Cells.

As shown in Figure 10 a, results obtained by the analysis of stiffness and viscosity data using Ting’s model, revealed that after 24 h of CB treatment a dose-dependent enhancement in the E 0 elastic modulus was found, suggesting a major cell stiffness; for the viscosity related parameter (α), an increasing trend was observed, suggesting a tendency of cells to become more fluid.

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Data reported in Figure 12 b showed a trend toward increased expression of ATG7 , LC3A and BECN1 in both DMSO- and CB-treated cells along the differentiation period, reaching statistical significance only in CB-treated cells.

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