Phospholipase D1 Attenuation Therapeutics Promotes Resilience against Synaptotoxicity in 12-Month-Old 3xTg-AD Mouse Model of Progressive Neurodegeneration.

Int J Mol Sci · 2023 · PMC9967100 · PMID 36834781

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failed to reach significanceno p-value reported

Our sex-stratified approach also uncovered that the inhibitor-treated male cohort failed to reach significance when compared to the saline-treated male group for the cued response.

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did not reach statistical significanceno p-value reported

The fEPSP slope as a function of FV did not reach statistical significance between the treatment groups ( Supplementary Figure S3G ) or when separated into males ( Supplementary Figure S3H ) and females ( Supplementary Figure S3I ), perhaps due to the increased variability within the saline-treated group.

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